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The Video of the Week now showing on Light After Life's Portal Page is: 'PSYCHIC' (Part 1 and 2)

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» Yahoo Mail down - again!
by Jamboree 21st February 2018, 23:42

» Wonderful images - fabulous music (Part 2)
by Kitkat 20th February 2018, 21:35

» Daughter fundraising to save her terminally ill mother
by Jamboree 18th February 2018, 11:53

» Kitkat's KK Blog
by Kitkat 15th February 2018, 21:36

» Keep a Word - Delete a Word
by Jamboree 15th February 2018, 19:31

» Poetry from the heart.
by Jamboree 12th February 2018, 07:46

» A Day in The Life of a Dictator - Documentary
by Jamboree 12th February 2018, 07:21

» Guess the word
by Whiskers 9th February 2018, 20:41

» A coconut in a coffin?
by Whiskers 9th February 2018, 20:35

» Books
by Stardust 9th February 2018, 16:11

» Limericks
by bimbow 8th February 2018, 21:22

» Stardust on the Moon
by Stardust 8th February 2018, 20:13

» Bureaucats: Whiskers in the Workplace
by Whiskers 4th February 2018, 12:21

» Is there a Cathy in the place?
by Kitkat 1st February 2018, 19:17

» Delicious and nutritious
by Stardust 1st February 2018, 14:38

» Chinese New Year
by Stardust 1st February 2018, 14:17

» Feather by the sea.
by Stardust 1st February 2018, 10:37

» Message in a bottle from 1980s resurfaces in 2018
by Kitkat 28th January 2018, 12:08

» What's your emergency?
by Whiskers 27th January 2018, 13:09

» YouTube free-loading vlogger gets a much needed lesson in reality
by Whiskers 22nd January 2018, 20:17

» Three-month-old baby says "hello"
by Kitkat 13th January 2018, 15:00

» The cartoon thread.
by bimbow 12th January 2018, 22:06

» 60 Christmas traditions around the world
by Kitkat 30th December 2017, 21:58

» Simon's Cat
by Kitkat 26th December 2017, 16:27

» A new(ish) song for Christmas.
by Whiskers 24th December 2017, 13:49

» Merry Christmas
by Whiskers 24th December 2017, 13:37

» The Christmas Thread
by Kitkat 20th December 2017, 21:22

» A reader's response to your article on food waste
by Whiskers 18th December 2017, 14:35

» Downward Dog
by Kitkat 4th December 2017, 21:35

» A very young Bee Gees treat
by Whiskers 29th November 2017, 16:35

» Prime cheek!
by Kitkat 28th November 2017, 09:32

» The life and achievements of Dr Elsie Inglis
by Kitkat 26th November 2017, 09:14

» Hidden disabilities: Pain beneath the surface
by Kitkat 21st November 2017, 21:20

» Scary photos
by Kitkat 19th November 2017, 12:50

» The 7-year-old neuroscientist wowing the internet
by Kitkat 16th November 2017, 10:03

» The cat killer stalking suburbia
by Whiskers 6th November 2017, 15:53

» It's that time again .....
by Kitkat 29th October 2017, 00:21

» Happy Halloween!
by Stardust 25th October 2017, 08:37

» Love makes the world go round
by Stardust 25th October 2017, 08:00

» Need help with homework (Hall Effect)
by Kitkat 24th October 2017, 12:18

» Well hello there!
by Whiskers 23rd October 2017, 23:53

» Madeleine McCann investigation continues ...
by Whiskers 23rd October 2017, 23:43

» Famous Youtubers... Do you watch them? Do you dislike them?
by Jamboree 23rd October 2017, 00:44

» Control your television with any object
by loner55 16th October 2017, 10:32

» Fahrenheit 451
by loner55 16th October 2017, 10:26

» HAPPY BIRTHDAY to Feather!
by Jamboree 15th October 2017, 17:43

» A walk through Dominica, hours after Hurricane Maria
by Kitkat 15th October 2017, 12:48

» SKEPS Forum
by Kitkat 8th October 2017, 22:00

» Quotes about Lifestye
by Whiskers 7th October 2017, 15:25

» MPs call for ESA death statistics to be published (Calum's List)
by Kitkat 30th September 2017, 18:23

» Songs from the heart
by Stardust 20th September 2017, 20:55

» Bodies of 'hundreds' of children buried in mass grave
by mac 19th September 2017, 12:25

» Psychics didn't foresee THAT coming!
by mac 16th September 2017, 15:14

» Number 7777
by Kitkat 14th September 2017, 14:10

» 'Messy' mum barred from pub
by Stardust 11th September 2017, 16:17

» [solved] Multiquote ?
by Whiskers 11th September 2017, 11:13

» Cosmic beauty
by Stardust 8th September 2017, 21:29

» Why men are happier people???
by Stardust 8th September 2017, 20:10

» A Granma's Anagrams
by Stardust 8th September 2017, 19:49

» Silly Endings.
by Stardust 8th September 2017, 19:45

» Pink rainbow
by Stardust 8th September 2017, 15:46

» Barking mad!
by Stardust 8th September 2017, 15:44

» Invasion of the sex-craved spiders! EEK!
by Stardust 8th September 2017, 15:38

» Surviving in Libya
by Kitkat 7th September 2017, 22:52

» The Forum Café
by Kitkat 7th September 2017, 14:53

» Hurricane Irma
by Kitkat 7th September 2017, 12:22

» Struggling To Login
by Kitkat 6th September 2017, 17:41

» Kitchen bat chase video goes viral
by Kitkat 6th September 2017, 17:21

» 10 things we didn't know last week ...
by Whiskers 4th September 2017, 14:31

» End of Summer Drinks
by EndoWarriror 1st September 2017, 13:53

» Bruce Forsyth dies aged 89
by EndoWarriror 1st September 2017, 13:34

» Notifications re new topics & posts on the forum
by Kitkat 1st September 2017, 13:23

» New forum design
by Jamboree 23rd August 2017, 13:03

» Photobucket
by Jamboree 10th August 2017, 02:36

» Hi from Brin
by Whiskers 6th August 2017, 12:14

» Delusions
by Kitkat 30th July 2017, 12:19

» BABY PLEASE DON'T GO ...
by Jamboree 25th July 2017, 16:03

» Wonderful images - fabulous music (Part 1)
by bimbow 21st July 2017, 22:21

» Photobucket no longer free ...
by Kitkat 8th July 2017, 11:05

» Problems logging in from your mobile, iPad or tablet?
by Kitkat 5th July 2017, 13:05

» Protest March through London
by Kitkat 1st July 2017, 17:41

» Our NHS
by Whiskers 29th June 2017, 16:49

» [solved] Forum showing me as online -- but I am not!
by Kitkat 25th June 2017, 10:41

» Day of Rage in London
by Kitkat 21st June 2017, 16:56

» NHS European Health Insurance Card
by Kitkat 20th June 2017, 21:26

» Postcards from the Shoutbox
by Whiskers 20th June 2017, 13:08

» Shout Box (SL and LAL)
by Kitkat 19th June 2017, 22:29

» A day out at the polling station
by Stardust 9th June 2017, 14:48

» Functions of the Blue Toolbar at top of the Forum
by Kitkat 5th June 2017, 10:47

» Light After Life forum's new address
by Kitkat 1st June 2017, 18:42

» Tick tock: The importance of knowing the right time
by Whiskers 1st June 2017, 11:23

» Derek Acorah to appear in Celebrity Big Brother 2017 ?
by Kitkat 24th May 2017, 22:38

» Publications
by Kitkat 22nd May 2017, 00:46

» The world's longest cat?
by Whiskers 19th May 2017, 09:22

» Nigeria
by Kitkat 19th May 2017, 08:54

» Redwater
by Kitkat 18th May 2017, 17:28

» Maggie's Cancer Care Centres
by Kitkat 17th May 2017, 18:07

» I'm being chased by an otter!
by Kitkat 16th May 2017, 13:07

» Eurovision Song Contest 2017
by Kitkat 16th May 2017, 11:49

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You know that headache you've got ....

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Kitkat
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You know that headache you've got ....

Post by Kitkat on 22nd November 2014, 12:46

Four years of excruciating seizures caused by the 1cm tapeworm found burrowing through a man's brain

surprised

It started with headaches, memory flashbacks and a strange sense of smell. It ended with doctors pulling a 1cm-long worm from the brain of man who had lived unwittingly with the parasite for at least four years.

The 50-year-old patient complained of various neurological symptoms including seizures and a progressive pain on his right side, which turned out to be a tapeworm burrowing from one side of his brain to the other.

Doctors at Addenbrooke’s Hospital in Cambridge recovered the tapeworm during an exploratory operation after an MRI scan had indicated that something worm-like could be behind the patient’s deteriorating condition.

Scientists at the nearby Wellcome Trust Sanger Institute carried out a genome analysis and found that the tapeworm belonged to a species called Spirometra erinaceieuropaei, which had never been seen before in Britain – and only 300 cases of which have been reported worldwide since 1953.

The tapeworm has a complex life cycle involving two or three different host species (NHS) The tapeworm has a complex life cycle involving two or three different host species (NHS)

During the four years that the patient was known to be suffering from symptoms, the worm had wriggled at least 5cm from one side of the brain to the other, crossing a sensory structure called the thalamus, scientists said.

The patient, a Chinese-born man who has lived in Britain for the past 20 years, has recovered well after surgery with the help of an anti-tapeworm drug. It is not known how he became infected, although it is likely to have been during one of his frequent visits to China, the researchers said.

“We did not expect to see an infection of this kind in the UK, but global travel means that unfamiliar parasites do sometimes appear,” said Effrossyni Gkrania-Klotsas, an infectious disease specialist at Addenbrooke’s NHS Trust.

“We can now diagnose sparganosis using MRI scans, but this does not give us the information we need to identify the exact tapeworm species and its vulnerabilities,” Dr Gkrania-Klotsas said.

“Our work shows that, even with only tiny amounts of DNA from clinical samples, we can find out all we need to identify and characterise the parasite,” she added.

The tapeworm has a complex life cycle involving two or three different host species. The patient could have become infected in a number of ways, either by eating infected fresh-water crustaceans or the undercooked meat of reptiles and amphibians, or possibly by using a Chinese remedy for sore eyes that involves a poultice made of raw frogs, the researchers said.

“We don’t know how it got into him. There is very little known about how it infects humans, and it can go anywhere once inside the body, [even] the eyeball or brain,” said Hayley Bennett of the Sanger Institute, the lead author of the study published in the journal Genome Biology.

“It can do a lot more damage when it’s in the brain, obviously. It managed to live for so long because we think it absorbs nutrients from the surrounding tissues,” Dr Bennett said.

“It remained in its larval form because it doesn’t develop into an adult when inside humans. This shows that humans are really an unintended, dead-end host for the parasite,” she said.

The ribbon-shaped worm did not have mouthparts or the tiny hooklets used as anchors, the usual adornments of adult tapeworms, but it nevertheless managed to live for several years on whatever food it found within the man’s head.

Its genome turned out to be about 10 times bigger than comparable tapeworms, and just a third of the size of the human genome. However, much of its DNA is filled with repetitive sequences that appear to be largely redundant, Dr Bennett said.

“We only had a minute amount of DNA available to work with, just 40 billionths of a gram. So we had to make difficult decisions as to what we wanted to find out from the DNA we had,” she said

“It was really quite unexpected to find that it has such a big genome. It has a lot of genes for proteases, the enzymes used to break down proteins,” she added.

Studying the genomes of parasites allows scientists to explore new ways of developing drugs and other forms of treatment, said Matt Berriman of the Wellcome Trust, a senior author of the scientific paper.

“For this uncharted group of tapeworms, this is the first genome to be sequenced and has allowed us to make some predictions about the likely activity of known drugs,” Dr Berriman said.

http://www.independent.co.uk/news/science/four-years-of-excruciating-seizures-caused-by-the-1cm-tapeworm-found-burrowing-through-a-mans-brain-9873672.html
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Re: You know that headache you've got ....

Post by Whiskers on 23rd November 2014, 11:00

scared  pale

Doesn't bare thinking about.  What a Face
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Stardust
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Re: You know that headache you've got ....

Post by Stardust on 26th November 2014, 14:20

I couldn't bring myself to read that, the title alone was bad enough. Yuk!
Shocked  pale


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